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Bioengineering research at OU focuses on basic and
applied research in both biochemical and biomedical
engineering. CBME faculty have conducted research
in the bioengineering area for many years.
This increased with
the creation of the Bioengineering Center.
The OU
Bioengineering Center was established
in 1999 with a $1 million grant from the Whitaker
Foundation. This Center fosters collaborative research
between the OU College of Engineering, the OU Health
Sciences Center, and the Oklahoma Medical Research
Foundation. Additional lab space for bioengineering was
activated in early 2005 with the completion
of the Stephenson Research Technical Center.
Focus areas of research include:
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application of genetic engineering to improve
the purification of proteins and peptides produced
by
microorganisms
-
design and production by recombinant
DNA technology of proteins that destroy or block
the spread
of cancer cells
-
application of biotechnology
to the remediation of contaminated water and
soil
-
role of fluid mechanical forces in disease
states of human vascular cells and in interaction
of
human vascular cells with circulating platelets
and white
blood cells
-
dissolution of blood clots
(thrombolysis) by plasminogen activators and
the development
of rheologic tests
to study thrombolysis
-
supercritical extraction
in food processing and drug purification
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tissue engineering
of small diameter blood vessels, bone and other
connective tissue
- biosensors
Research equipment
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fermentation and tissue culture bioreactors
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autoclaves
-
biological safety hood
-
sonication equipment for
breaking cell membranes
-
DNA sequencer
-
electrophoresis equipment for the
analysis of DNA and proteins
-
high-performance
liquid chromatography system
-
high speed centrifuge
-
UV-visible spectrophotometer
-
-30C and -80C freezers
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CO incubator
-
tissue culture microscope
-
fluorescence video
microscopy system
-
cell counter and diluter
-
erythrocyte deformability
apparatus
-
sub-micron particle analyzer
-
capillary viscometer
-
couette viscometer
-
damped oscillation viscometer
-
oxygen content
analyzer
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filtrometer
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AFM
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flourescence microscopy with image analysis
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